Go for it, says Mark Benden, Ph.D., of Texas A&M's Health Science Center.
Among the benefits: better cholesterol and blood glucose levels, more calories burned, improved blood flow and breathing, and stronger core muscles.
Standing, he says, also allows you to maintain the natural S curve in your spine, which results in less back pain than sitting. "It's hard to maintain correct posture in a chair," he says. "It fights our basic biomechanics."
Another bonus: You may be more mindful. "You think better on your feet than on your seat," he adds. "Studies show better responsiveness, alertness, and reaction speed."
Ideally, the height of the desk should allow your elbows to rest at about 90-degree angles while you type.